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SNP: rs7607980

linkouts : SNPedia

Nearby Genes

COBLL1 - cordon-bleu WH2 repeat protein-like 1

GRB14 - growth factor receptor-bound protein 14
The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]


Associated Traits (number of studies)

Fasting insulin-related traits (interaction with BMI) (1)

Association Studies

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Positive
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Search Results from Open Access Papers

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