Replication and Predictive Value of SNPs Associated with Melanoma and Pigmentation Traits in a Southern European Case-Control Study

... (P=0.411 for Mann-Whitney U). 10.1371/journal.pone.0055712.g001 Figure 1 Correlation of effect sizes. Correlation of the effect sizes found in the Greek population and those described in the original publication or MelGene..Not shown are: rs4636294 (excluded from analyses because of HWE deviation); rs1011970 because OR was not available in the original publication and/or MelGene; rs1805009 and rs11547464 because all subjects were homozygous for the major allleles. When limited to SNPs that had

... median frequency in HapMap CEU was 32% (IQR, 1262%) (P=0.243 for Mann-Whitney U). The correlation between the two populations was very high (r=0.95, P<0.0001) ( Fig. 2 ). 10.1371/journal.pone.0055712.g002 Figure 2 Correlation of risk allele frequencies. Correlation of the risk allele frequencies found in the Greek population and the frequencies of the same alleles from the HapMap CEU sample. Not shown are: rs4636294 (excluded from analyses because of HWE deviation); rs1805009 and rs11547464 because

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