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SNP: rs1421085

linkouts : SNPedia

Nearby Genes

FTO - fat mass and obesity associated
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]


Associated Traits (number of studies)

Obesity (2)Obesity (early onset extreme) (1)Dietary macronutrient intake (1)

Association Studies

Reported
Allele
Positive
Allele
Effect Size /
Odds Ratio
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Trait Study



Search Results from Open Access Papers

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