Gene: SERPINA1 - serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 - (NCBI)

The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]